Does resveratrol work on melasma ?


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RESVERATROL

What is resveratrol?

It is a type of compound produced by plants in response to injury or attack. It is present in some foods, including red wine, and the skin of grapes, blueberries, raspberries and peanuts. Resveratrol is used in the treatment of high cholesterol, heart disease, cancer, and many other serious conditions.

What is it best for?

When applied to the skin, it helps protect it from environmental factors such as pollution. It also brightens skin and minimizes redness due to its skin-calming properties. Resveratrol has antioxidant, anti-inflammatory, and wound-healing properties, which means it can be used to treat acne. It reduces pigmentation caused by UV rays as well.

What is the drawback?

While there are a number of side effects caused by taking resveratrol orally, the only downside of applying it topically is that it slows down the blood clotting process, so people with bleeding disorders should avoid using it. Do not use resveratrol in any form if you are about to undergo surgery. Ask your doctor for more details.


MELASMA

What is melasma?

Melasma is a specific example of hyperpigmentation. Melasma looks like whole patches of brown or darker skin across the parts of the face and neck. Melasma is common among women who are pregnant - it’s even referred to as “the mask of pregnancy.”  But melasma can occur in both men and women who are not pregnant, too. Melasma can be caused by UV damage, but there are also genetic, hormonal, and medication-induced causes for melasma, too.

What ingredients are best for melasma?

There are a variety of topical ingredients that can be used to lighten the skin from melasma or reduce its appearance. Each ingredient works in different ways, and each has their own benefits and drawbacks.  hydroquinone, arbutin, vitamin C (ascorbic acid, and tetrahexyldecyl ascorbate, etc) are some of the most commonly used ingredients for melasma treatment. 

Hydroquinone is a skin lightening cream that works by suppressing the production of melanin. There are drawbacks to using hydroquinone, however, including cancer risks demonstrated by recent scientific studies, as well as  hydroquinone-induced ochronosis. 

Arbutin is a synthesized derivative of hydroquinone. It acts as a powerful skin lightening ointment that works a bit differently than hydroquinone. It blocks the production of melanin instead of “bleaching” the skin. 

Vitamin C can be used as a brightening agent to lighten the hyperpigmentation of your sunspots or melasma. It works by inhibiting the enzyme tyrosinase, preventing the formation of melatonin. 

Ascorbic Acid is actually the formal scientific name for one form of Vitamin C.  It can refer to either a naturally occurring Vitamin C found in foods such as citrus, or a synthetic form of ascorbic acid created to be more shelf-stable for skincare products like discoloration repair lotions and creams. 

Tetrahexyldecyl Ascorbate is another form of Vitamin C.  By synthesizing this compound from Vitamin C, dermatologists are able to give us all the benefits of Vitamin C in a more shelf-stable form that can also be soluble in oil to make more effective, deeper penetrating skin products.  (Herndon 2016)

Ingredients in the vitamin A family (ie. Retinol, tretinoin, etc) and acids (glycolic acid, lactic acid, salicylic acid) help damaged pigmented skin cells shred faster, so they also help with melasma. 


Does resveratrol work on melasma ?

resveratrol may be effective for melasma, but there are many other factors that may affect whether this ingredient would work on your skin or if there are better ingredients that may work for you. Take this skin quiz to find the best ingredients for your skin and build your skincare routine.


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